国际眼科纵览 ›› 2021, Vol. 45 ›› Issue (4): 273-279.doi: 10.3760/ cma.j.issn.1673-5803.2021.04.001

• 综述 •    下一篇

青光眼手术的分类及进展

李翔骥1 贺翔鸽2 朱小敏1 敬晋1 王薇2 谢琳1   

  1. 1重庆医科大学附属第三医院眼科 400016;2 爱尔眼科集团重庆爱尔眼科医院 400020
  • 收稿日期:2020-09-30 出版日期:2021-08-22 发布日期:2021-08-30
  • 通讯作者: 谢琳,Email:xielin@hospital.cqmu.edu.cn E-mail:xielin@hospital.cqmu.edu.cn
  • 基金资助:
    国家自然科学基金(81670860);重庆市自然科学基金(cstc2018jcyjAX0016)

Classification and progress of glaucoma surgery

Li Xiangji1, He Xiangge2, Zhu Xiaomin1, Jing Jin1, Wang Wei2, Xie Lin1   

  1. 1 Department of Ophthalmology, The Third Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China; 2 Chongqing Aier Eye Hospital of Aier Eye Hospital Group, Chongqing 400020, China
  • Received:2020-09-30 Online:2021-08-22 Published:2021-08-30
  • Contact: Xie Lin, Email: xielin@hospital.cqmu.edu.cn E-mail:xielin@hospital.cqmu.edu.cn
  • Supported by:
    National Natural Science Foundation of China (81670860); Natural Science Foundation of Chongqing(cstc2018jcyjAX0016)

摘要: 手术治疗是青光眼治疗的重要手段。本文将目前已经和未来即将应用于临床的主要青光眼手术方式,根据不同降眼压机制分为增加房水引流和减少房水生成两大类。根据房水引流途径,将增加房水引流类分为外引流和内引流两个手术亚类,并将内引流进一步分为Schlemm管途径引流和脉络膜上腔途径引流。减少房水生成类手术分为睫状体光凝术、超声睫状体成形术、睫状体冷凝术三个亚类。目前,在外引流手术方面,复合式小梁切除术仍是主流手术方式,多种类型青光眼引流装置也已广泛临床应用。内引流手术方面,以Schlemm管为引流途径的手术方式中,内外路微导管辅助360°小梁切开术、各式内路小梁切开刀、微支架逐渐应用于临床,并取得良好的手术效果;以脉络膜上腔为引流途径植入装置的安全性和有效性仍需进一步验证。新型以减少房水生成为目的手术方式变得更加安全、可控,已不再局限于治疗无视力的晚期青光眼患者。(国际眼科纵览,2021, 45: 273-279)

关键词: 青光眼/外科学, 青光眼滤过手术, 青光眼引流装置, 微创青光眼手术

Abstract: Surgery is an important intervention in treatment of glaucoma. In this article, according to the different mechanisms of intraocular pressure (IOP) lowering classifies the surgical procedures into two categories: increasing drainage of aqueous humor and reducing the generation of aqueous humor. Additionally, the basis of the drainage pathways, divides the increasing drainage of aqueous humor type into two subtypes: external drainage and internal drainage which includes Schelemm canal drainage approach and suprachoroidal space drainage approach. Reducing the generation of aqueous humor is divided into three subtypes: cyclophotocoagulation, ultrasond cycloplasty (UCP), cyclocryotherapy. Currently, combined trabeculectomy remains the mainstream procedure of external drainage surgery and various glaucoma drainage devices have been used in clinic. In terms of internal drainage surgery, among the procedures of Schlemm canal drainage approach, internal or external 360°transluminal trabeculotomy, trabeculotomes and microstents have been gradually applied in clinic, and achieve excellent surgical outcome. The safety and efficacy of the implant devices relying on suprachoroidal space drainage approach need further studies. New types of aqueous humor generation reduction procedure are becoming safer and controllable and no longer limited to the treatment of blind advanced glaucoma patient. (Int Rev Ophthalmol, 2021, 45: 273-279)

Key words: glaucoma/surgery, glaucoma filtration surgery, glaucoma drainage device, minimally invasive glaucoma surgery